Beryl J. Ortwerth
Professor Emeritus of Opthalmology
Joint Emeritus Professor of Biochemistry
E-mail:ortwerthb@missouri.edu
Office: C-112 Eye Institute East
Mail: Eye Institute - East
404 Portland Street
Columbia, MO 65201
Phone: 573-882-6092
Educational background
| Degree | School | Location | Major |
| BS | St. Louis University | St. Louis, Mo. | Chemistry |
| MS | University of Missouri | Columbia, Mo. | Biochemistry |
| PhD | University of Missouri | Columbia, Mo. | Biochemistry |
Notable honors and service
- Cataract Program Planning Committee, 1982
- Full member Visual Sciences A1 Study Section, 1986-92
- Alcon Distinguished Scientist Award, 1988
Selected publications
Argirov, O.K., Lin, B. and Ortwerth, B.J., 2-Ammonio-6-(3-oxidopyridinium-1-yl)hexanoate (OP-lysine) is a newly identified advanced glycation endproduct in cataractous and aged human lenses. J. Biol. Chem. 279:6487-6495 (2004).
Cheng, R., Feng, Q., Argirov, O.K. and Ortwerth, B.J., Structure elucidation of a novel yellow chromophore from human lens protein. J. Biol Chem. 279:45441-45449 (2004).
Cheng, R., Feng, Qi and Ortwerth, B.J., LC-MS display of the total modified amino acids in cataract lens proteins and in lens proteins glycated by ascorbic acid in vitro. Biochim. Biophys. Acta 1762:533-543 (2006).
Fan, X., Reneker, L.W., Obrenovich, M.E., Strauch, C., Cheng, R., Jarvis, S.M., Ortwerth, B.J., and Monnier, V.M., Vitamin C mediates chemical aging of lens crystallins by the Maillard reaction in a humanized mouse model. Proc. Natl. Acad. Sci. U.S.A. 103:16912-16917 (2006).