Biochemistry

Structural biology: X-ray crystallography of medically important proteins.

Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.

Medical education.

Predicting RNA structures and structural changes; Computational studies of RNA thermal stability and folding kinetics.

Combinatorial biology applied to cancer detection and therapy.

Enzymology, physiology and genomics of biological nitrogen fixation and related metabolic activities.

Nucleotide receptors in inflammation and wound healing.

Gene expression and replication; plant nutritive improvement and medical uses.

Biochemistry education.

Mechanisms of DNA damage by synthetic and naturally occurring antitumor agents, toxins and mutagens.

Transcriptional control by auxins in plants; plant RNA polymerases.

Control of gene expression by plant growth regulators.

BTB-Kelch substrate adaptor family in development, oncogenesis and neurodegeneration.

Transmembrane receptors and sensory transduction in bacterial chemotaxis.

Membrane trafficking in plant innate immunity.

Biophysical characterization of EF-hand calcium-binding proteins; protein-ligand interactions.

Biochemical genetics and epigenetics of estrogens and related receptors.

Transcriptional control in mitochondrial biogenesis and oxidative stress

Carbohydrates in cancer and bacterial infection; cancer prevention and treatment; host-pathogen interactions in cystic fibrosis; analytical methodologies.

Cell-cell interactions in pollen recognition and rejection.

Protein targeting and folding in plants, organelle biogenesis, posttranslational modifications.

Proteomics of protein expression and assembly; metabolic engineering.

Medical education.

Carbohydrates and cancer.

Biochemical and physiological function of trace elements. Metabolism and bioavailability of trace elements.

Proteomics of protein phosphorylation and protein kinases; signaling and secretion during host-pathogen interactions.

RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.

Biochemistry education.

Regulation of metal nutrition and impacts on common human diseases.

Collagen in inherited and acquired diseases of bone and kidney; matrix metalloproteinases; medical genetics.

Cancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging.

Metabolism, signal transduction, protein kinases and phosphorylated proteins in plants.

Molecular chaperones in protein export; analysis of protein-protein interactions.

Reproductive biology: signaling between conceptus and uterus; stem cells.

Combinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.

Structure-function of crystallins, role of ocular proteases and molecular basis for cataract development.

Students' use of scientific evidence, instructional decision making, classroom assessment, English language learners, design of instructional materials.

Glutamate receptors in learning and memory. Ischemic induction of inflammatory factors and treatment with polyphenols.

Functional genomics of plant-microbe interactions and plant development.

Neurodegenerative diseases, signal transduction, phospholipases A2, oxidative stress, anti-inflammatory and anti-oxidant botanical compounds.

Spatial and temporal characterization of macromolecular dynamics involved in protein complexes and signaling pathways.

X-ray crystallography of proline metabolic enzymes, bacterial virulence proteins and anti-DNA antibodies; structural bioinformatics of protein-bound water; molecular dynamics simulations of biological molecules.

Proteomics and phosphoproteomics of seed development and metabolism in oilseeds.

Mechanistic enzymology applied to agriculturally and medically important enzymes.

Transcriptional regulation in striated muscle during development, activity, and stress; transgenic mouse models.

Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.

Radiopharmaceuticals for therapy and imaging; nuclear medicine.

Environmental microbiology; bioremediation of toxic metal; genetics and biochemistry of sulfate-reducing bacteria

Nucleotide receptors and signaling in inflammation, cardiovascular and autoimmune exocrine disease.

MAP kinases and signaling in plant defense responses.

Protein-ligand interactions, protein-protein interactions, computer-aided drug design and modeling of quantitative structure-function relationships of membrane proteins.