July 2008 News
July 31, 2008
Agnes Simonyi's lab
New grant award
NCCAM/NIH grant titled “Neuroprotection of apocynin from Picrorhiza kurroa in cerebral ischemia” 06/01/08-05/31/10 Total: $403,205
New publications
Christoffersen, G.R.J., Simonyi, A., Schachtman, T.R., Clausen, B., Clement, D., Bjerre, V.K. Mark, L.T., Reinholdt, M., Schmith-Rasmussen, K. and Zink, L.V.B. (2008) MGlu5 antagonism impairs exploration and memory of spatial and non-spatial stimuli in rats. Behavioural Brain Research, 191:235-245.
Ngomba, R.T., Ferraguti, F., Badura, A., Citraro, R., Battaglia, G., Bruno, V., De Sarro, G., Simonyi, A., van Luijtelaar, G. and Nicoletti, F. (2008) Positive allosteric modulation of metabotropic glutamate 4 (mGlu4) receptors enhances spontaneous and evoked absence seizures. Neuropharmacology, 54:344-354.
Steve Van Doren's lab
New grant award
American Heart Association (Midwest Affiliate), "Docking of Matrix Metalloproteinase-12 with a Triple Helical Peptide from Collagen V"
New publications
Bhaskaran R*, Palmier M*, Lauer-Fields JL, Fields GB, and Van Doren SR. (2008) MMP-12 Catalytic Domain Recognizes a Triple-Helical Peptide Model of Collagen V with Exosites and High Activity. Journal of Biological Chemistry. In press. * contributed equally
Liang X and Van Doren SR. (2008) Mechanistic Insights into Phosphoprotein-Binding FHA Domains. (Review). Accounts of Chemical Research. In press.
Van Doren SR, Wei S, Gao G, Dague BB, Palmier MO, Bahudhanapati H, and Brew K. (2008) Inactivation of N-TIMP-1 by N-Acetylation when Expressed in Bacteria. Biopolymers. In press.