Structural and Chemical Biology faculty
- Lesa J. Beamer
Structural biology: X-ray crystallography of medically important proteins.
- Donald H. Burke
Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.
- Shi-jie Chen
Predicting RNA structures and structural changes; Computational studies of RNA thermal stability and folding kinetics.
- Peter V. Cornish
RNA biochemistry, single molecule fluorescence, NMR, RNA folding and dynamics.
- Susan L. Deutscher
Combinatorial biology applied to cancer detection and therapy.
- Kent Gates
Mechanisms of DNA damage by synthetic and naturally occurring antitumor agents, toxins and mutagens.
- Gerald Hazelbauer
Transmembrane receptors and sensory transduction in bacterial chemotaxis.
- Michael Henzl
Biophysical characterization of EF-hand calcium-binding proteins; protein-ligand interactions.
- Gavin M. King
Single molecule biophysics.
- Thomas P. Mawhinney
Carbohydrates in cancer and bacterial infection; cancer prevention and treatment; host-pathogen interactions in cystic fibrosis; analytical methodologies.
- Brenda A. Peculis
RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.
- Thomas P. Quinn
Cancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging.
- Linda Randall
Molecular chaperones in protein export; analysis of protein-protein interactions.
- Stefan G. Sarafianos
Molecular mechanisms of drug resistance and inhibition of HIV, SARS, and other viral and bacterial pathogens.
- Frank J. Schmidt
Combinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.
- John J. Tanner
X-ray crystallography of proline metabolic enzymes, bacterial virulence proteins and anti-DNA antibodies; structural bioinformatics of protein-bound water; molecular dynamics simulations of biological molecules.
- Peter A. Tipton
Mechanistic enzymology applied to agriculturally and medically important enzymes.
- Steven R. Van Doren
Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.
- Xiaoqin Zou
Protein-ligand interactions, protein-protein interactions, computer-aided drug design and modeling of quantitative structure-function relationships of membrane proteins.