Biochemistry

Structural and Chemical Biology faculty

• Lesa J. Beamer
  Structural biology: X-ray crystallography of medically important proteins.
• Donald H. Burke
  Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1.
• Shi-jie Chen
  Predicting RNA structures and structural changes; Computational studies of RNA thermal stability and folding kinetics.
• Peter V. Cornish
  RNA biochemistry, single molecule fluorescence, NMR, RNA folding and dynamics.
• Susan L. Deutscher
  Combinatorial biology applied to cancer detection and therapy.
• Kent Gates
  Mechanisms of DNA damage by synthetic and naturally occurring antitumor agents, toxins and mutagens.
• Gerald Hazelbauer
  Transmembrane receptors and sensory transduction in bacterial chemotaxis.
• Michael Henzl
  Biophysical characterization of EF-hand calcium-binding proteins; protein-ligand interactions.
• Gavin M. King
  Single molecule biophysics.
• Thomas P. Mawhinney
  Carbohydrates in cancer and bacterial infection; cancer prevention and treatment; host-pathogen interactions in cystic fibrosis; analytical methodologies.
• Brenda A. Peculis
  RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis.
• Thomas P. Quinn
  Cancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging.
• Linda Randall
  Molecular chaperones in protein export; analysis of protein-protein interactions.
• Stefan Sarafianos
  Molecular mechanisms of drug resistance and inhibition of HIV, SARS, and other viral and bacterial pathogens.
• Frank J. Schmidt
  Combinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world.
• John J. Tanner
  X-ray crystallography of proline metabolic enzymes, bacterial virulence proteins and anti-DNA antibodies; structural bioinformatics of protein-bound water; molecular dynamics simulations of biological molecules.
• Peter A. Tipton
  Mechanistic enzymology applied to agriculturally and medically important enzymes.
• Steven R. Van Doren
  Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases.
• Xiaoqin Zou
  Protein-ligand interactions, protein-protein interactions, computer-aided drug design and modeling of quantitative structure-function relationships of membrane proteins.