Structural and Chemical Biology faculty
- Lesa J. Beamer
Structural biology: X-ray crystallography of medically important proteins. - Donald H. Burke
Ribozyme mechanism and evolution and the origin of life; antiviral nucleic acid aptamers and the molecular basis of drug resistant HIV-1. - Shi-jie Chen
Predicting RNA structures and structural changes; Computational studies of RNA thermal stability and folding kinetics. - Susan L. Deutscher
Combinatorial biology applied to cancer detection and therapy. - Kent Gates
Mechanisms of DNA damage by synthetic and naturally occurring antitumor agents, toxins and mutagens. - Gerald Hazelbauer
Transmembrane receptors and sensory transduction in bacterial chemotaxis. - Michael Henzl
Biophysical characterization of EF-hand calcium-binding proteins; protein-ligand interactions. - Thomas P. Mawhinney
Carbohydrates in cancer and bacterial infection; cancer prevention and treatment; host-pathogen interactions in cystic fibrosis; analytical methodologies. - Brenda A. Peculis
RNA processing, RNA stability, RNA turnover, RNA decapping enzymes, snoRNPs required for ribosome biogenesis. - Thomas P. Quinn
Cancer diagnostics, radiopharmaceutical imaging and therapy; cell and molecular imaging. - Linda Randall
Molecular chaperones in protein export; analysis of protein-protein interactions. - Frank J. Schmidt
Combinatorial chemistry of RNA and antimicrobial peptides; the prebiotic RNA world. - Chun Tang
Spatial and temporal characterization of macromolecular dynamics involved in protein complexes and signaling pathways. - John J. Tanner
X-ray crystallography of proline metabolic enzymes, bacterial virulence proteins and anti-DNA antibodies; structural bioinformatics of protein-bound water; molecular dynamics simulations of biological molecules. - Peter A. Tipton
Mechanistic enzymology applied to agriculturally and medically important enzymes. - Steven R. Van Doren
Structural biology: NMR investigations of protein structure, dynamics and protein-protein interactions, particularly proteins important in inflammatory diseases. - Xiaoqin Zou
Protein-ligand interactions, protein-protein interactions, computer-aided drug design and modeling of quantitative structure-function relationships of membrane proteins.
